The objectification of traditional Chinese medicine(TCM) syndromes has long been a key focus and challenge in the modernization of TCM research，gradually evolving into an important branch under the research paradigm of “combination of disease and syndrome”.In recent years，the TCM field has developed a relatively mature methodological system based on the principles，methods，and techniques of psychometrics.The critical steps mainly include the construction of an item pool，item selection，item weighting，determination of diagnostic thresholds，scale evaluation，and scale validation and application.From the perspective of development pathways for syndrome objectification，future research should be driven by artificial intelligence and focus on integrative analysis across multiple dimensions of information.Only by combining TCM's macro-level syndrome differentiation system with the micro-level syndrome differentiation approach of modern systems biology-centered on molecular biomarkers-can the essence of TCM syndromes be more comprehensively and systematically revealed，thereby exploring suitable approaches and methods for objective and standardized syndrome diagnosis.