Alzheimer's disease(AD) is a neurodegenerative disorder characterized by progressive cognitive impairment and neuropsychiatric symptoms.The aggregation of β-amyloid(Aβ) and abnormal phosphorylation of Tau protein are key mechanisms involved in AD pathogenesis.In recent years，impaired synaptic plasticity has been recognized as a major pathological feature of AD and a principal contributor to cognitive dysfunction.Currently approved anti-AD drugs can only alleviate some cognitive symptoms and fail to effectively slow disease progression.Studies have shown that traditional Chinese medicine(TCM) can mitigate synaptic ultrastructural damage，regulate synaptic transmission efficiency，modulate ligand-receptor interactions，and enhance the expression of synapse-associated proteins，thereby improving learning and memory deficits in AD models.However，comprehensive systematic reviews on this topic remain limited