从“气血失调”到“形质结构”论治噎膈的沿革和中医学模式的转变
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国家自然科学基金项目(82274609,82074338,82174465,82174463);中央高水平中医医院临床研究和成果转化能力提升项目-传承名老中医药专家学术经验专项(HLCMHPP2023012);中国中医科学院科技创新工程项目(CI2021B009);北京市自然科学基金项目(7212189);国家中医药管理局中医药创新团队项目(ZYYCXTD-C-202205);中国中医科学院优秀青年科技人才(创新类)培养专项(ZZ13-YQ-023);广安门医院续航工程青年拔尖人才培育项目(CZ40908)


From “Dysregulation of Qi and Blood” to “Morphology Structure”:Evolution of Dysphagia Treatment and Transformation of Traditional Chinese Medicine Medical Models
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    摘要:

    噎膈是指食物吞咽噎塞不顺的病证,其重症对应食管癌在内的多种肿瘤疾病。早期中医医家多从气机失常、胃阴亏耗、气虚阳微等“气血失调”层面论治疗噎膈。自朱震亨至张锡纯等历代医家在前代医家的基础上,逐步阐释了“瘀”“痰”在噎膈病中形成积聚并对脘管的“形质结构”造成改变的病机。而在以噎膈为代表的癌肿类疾病的认知过程中,中医学也体现了从自然哲学医学模式发展到机械论医学模式的部分转变。本文基于中医学认识噎膈病的历史沿革,通过分析中医学从“气血失调”到“气血失调-形质结构”并重的诊治思路,探讨中医学对肿瘤形质类、积聚类疾病的认识过程,为日后进一步优化对噎膈病病因和辨证的认识提供新的研究方向。

    Abstract:

    Dysphagia refers to the syndrome of choking when swallowing food and encompasses severe pathologies,including esophageal cancer and other tumors.Early traditional Chinese medicine(TCM) physicians treated dysphagia from the “dysregulation of qi and blood” level,such as disrupted qi movement,stomach yin depletion,and yang-qi deficiency.From ZHU Zhenheng to ZHANG Xichun,successive physicians expanded this understanding by elucidating how “blood stasis” and “phlegm” contribute to pathological accumulations that progressively change the morphological structure of the esophageal tract.In the understanding of cancer represented by dysphagia,TCM also demonstrates a partial shift from the natural philosophy-based medical model toward a mechanistic medical model.By analyzing the evolution of TCM clinical approaches—from a singular focus on “dysregulation of qi and blood” to a dual emphasis on “dysregulation of qi and blood and morphological-structural pathology” —this study explored TCM's conceptual progression in understanding tumor morphological entities and mass-forming disorders.This study provides new research directions for future optimization of the understanding of the etiology and pattern differentiation in dysphagia.

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孙天恒,秦英刚,刘瑞,花宝金.从“气血失调”到“形质结构”论治噎膈的沿革和中医学模式的转变[J].世界中医药,2025,(08).

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  • 收稿日期:2024-03-18
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  • 在线发布日期: 2025-06-17
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