Diabetic foot wound(DFW) is one of the most common serious complications of diabetes，which is prolonged，difficult to heal，and recurrent.In severe cases，there are risks of toe and limb amputation.In recent years，traditional Chinese medicine(TCM) has achieved remarkable efficacy in treating diabetes mellitus and its complications，and the treatment of DFW by TCM has become a difficult and hot topic to solve in research.Moreover，the establishment of a standardized animal model combining disease and syndrome is conducive to pathogenesis elucidation，new preparation development，and potential therapeutic target search，which provides a new theoretical and experimental basis for the promotion of the repair and treatment of DFW with TCM.By inquiring about relevant data，this paper summarized the existing animal models of dampness-heat toxin excess，cold-dampness-blocking collateral，blood stasis，and qi-yin deficiency syndromes.Then，this paper analyzed the specific processes and methods of modeling，as well as the pathogenesis characteristics of the corresponding types.Additionally，the paper discussed the specific DFW types，syndrome characteristics，modeling modes，and observational indexes.The problems of the current DFW modeling were also put forward，with the future DFW research directions and ideas being envisioned.This paper aims to provide references for the modeling of animal studies on TCM syndrome differentiation and provide new ideas for TCM treatment.