| 引用本文:王 斌 沈 毅.参茸助阳丸治疗肾阳亏虚型勃起功能障碍的临床与实验研究[J].世界中医药,2006,1(1):. |
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| 参茸助阳丸治疗肾阳亏虚型勃起功能障碍的临床与实验研究 |
| Clinical and Experimental Study on Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) for Treatment of Erectile Dysfunction Due to Kidney Yang Deficiency |
| 投稿时间：2006-09-14 |
| DOI： |
| 中文关键词: 勃起功能障碍/中医药疗法 @ 参茸助阳丸 |
| English Keywords:Erectile dysfunction/Chinese medical therapy @ Shenrong Zhuyang Wan(Shenrong Zhuyang Pills) |
| 基金项目: |
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| 中文摘要: |
| 目的：观察参茸助阳丸治疗肾阳亏虚型功能性勃起功能障碍的临床疗效。方法：121例患者随机分为两组，分别用参茸助阳丸(60例)和五子衍宗丸(61例)治疗，8周后对相关指标进行观察。建立肾阳虚动物模型，分别给予大、中、小剂量参茸助阳丸、大剂量强肾片和蒸馏水，观察用药前后动物性器官指数、阴茎勃起潜伏期、单位时间内交配次数和低温条件下生存时间等指标变化。结果：参茸助阳丸组近期治愈7例，显效28例，有效20例，无效5例，总有效率91.67%，总有效率和对疲乏无力、畏寒肢冷2组症状的改善优于对照组，无毒副作用。参茸助阳丸能够提高去势大鼠阴茎对外部刺激的兴奋性，可缩短动物阴茎勃起潜伏期；与去势模型对照组相比较可提高精囊+前列腺、提肛肌脏器指数；可使大鼠交配能力明显增强，单位时间内完成的扑捉及射精次数增加。参茸助阳丸大剂量组能够明显延长阳虚证小鼠在8℃条件下低温游泳存活时间。结论：通过临床观察和动物实验，参茸助阳丸对肾阳亏虚型功能性勃起功能障碍有较好的疗效，可以改善机体的肾阳虚证候。 |
| English Summary: |
| To observe the clinical curative effect of Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) on treating erectile dysfunction due to kidney yang deficiency.Methods: 121 cases of erectile dysfunction were randomly divided into Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) group (60 cases,treated by Shenrong Zhuyang Wan) and Wuzi Yanzong Wan (Wuzi Yanzong Pills) group (61 cases,treated by Wuzi Yanzong Wan),and the relevant indexes were observed after 8 weeks.Besides,animal models with kidney yang deficiency were set up and given different doses of Shenrong Zhuyang Wan(Shenrong Zhuyang Pills)(large dose,mediate dose and small dose) as well as a great amount of Qiangshen Pian (Qiangshen Tablets) and distilled water respectively,so as to observe the changes of indexes before and after medication,including changes of genital organ index,incubation period for penile erection,copulation times in a unit time and survival time in low temperature,etc.Results: In Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) group,7 cases were cured,28 cases got obvious curative effects,20 cases got positive effects and 5 cases with no obvious effect,and total effective rate being 91.67%.As far as total effective rate and improvements of symptoms of fatigue and short of strength as well as aversion to cold and cold limbs were concerned,Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) group was better than control group.Besides,Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) group was turned out to be non toxic and no side effects.Shenrong Zhuyang Wan (Shenrong Zhuyang Pills) could improve the penis excitability of caponized rats towards external stimulus and shorten incubation period for penile erection.Compared to those of caponized rats of control group,the index number of samenblase plus prostate and organs as well as levator ani muscle of rats of Shenrong Zhuyang Wan(Shenrong Zhuyang Pills) group were enhanced,the copulation ability was obviously improved and the number of times of capture and ejaculation in a unit time was increased.In Shenrong Zhuyang Wan(Shenrong Zhuyang Pills) group of large dose,the survival time of swimming under a low temperature of 8℃ of rats with yang deficiency syndrome could be obviously prolonged.Conclusion: Being proved by clinical observation and animal experiment,Shenrong Zhuyang Wan(Shenrong Zhuyang Pills) has good curative effect on erectile dysfunction due to kidney yang deficiency and it can improve kidney yang deficiency syndrome. |
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