| To investigate characteristics of the symptoms and signs in Chinese medicine of mild cognitive impairment (MCI) of elder people,and to provide evidences of syndromes differentiation for Chinese medical intervention and treatment.Methods:Patients with remembrance breakdown as chief complaint were selected for observation according to the standard by Petersen etc (1999).On the basis of studies on literatures over successive dynasties,basic syndrome types were set up,i.e.a) Syndrome of kidney deficiency,b)Syndrome of spleen qi deficiency,c) Syndrome of heart blood deficiency,d) Syndrome of turbid phlegm,e) Syndrome of blood stasis,f) Syndrome of liver depression.Clinical observation form for Mild Cognition Impairment (MCI) were established,including measuring scale of western medicine as well as a questionnaire of Chinese medical syndromes and signs,accordingly,44 selected MCI cases were differentiated for syndromes.Results:44 MCI cases mostly belonged to a),then c),e),b),d) in order,as none of f) had been discovered.Deficiency and excess in complexity accounted for 68.2%,haplo-syndrome for 9.1%,di-syndromes for 34.1%,tri-syndromes for 56.8% respectively.Significant differences (P<0.05) were shown in c) and b) between MCI and normal groups,while no significant differences (P>0.05) had been shown in any other syndrome types between the two groups.Conclusion:CMI is deficiency in root cause and excess in syndrome:it is based on deficiency of kidney,heart,and spleen in combination with excessive pathogenic factors,such as phlegm and stasis.Heart blood deficiency and spleen qi deficiency might be main pathogenic causes for cognitive impairment.These findings provided objective epidemiologic data for differentiation of syndromes for MCI of elder people,thus are remarkable in exploring effective methods of Chinese medical intervention. |
