| 引用本文:刘译鸿，徐凯，陈达灿.仙龙定痛饮治疗骨转移癌痛的临床观察[J].世界中医药,2007,2(5):. |
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| 仙龙定痛饮治疗骨转移癌痛的临床观察 |
| Clinical Observation of Xianlong Dingtong Yin on Osseous Metastasis Caused Pain |
| 投稿时间：2007-03-16 |
| DOI： |
| 中文关键词: 骨转移癌疼痛/中医药疗法 @ 仙龙定痛饮 |
| English Keywords:Osseous metastasis caused pain/Chinese medical therapy @ Xianlong Dingtong Yin |
| 基金项目: |
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| 中文摘要: |
| 目的：通过随机对照研究，探讨仙龙定痛饮治疗骨转移癌疼痛的临床疗效。方法：选择60例各类骨转移癌患者随机分为治疗组30例和对照组30例。治疗组予仙龙定痛饮+美施康定，对照组单纯予美施康定。两组治疗疼痛缓解有效率达50%(CR+PR)时，观察比较两组治疗前后生活质量变化(PS评分、FLIC量表)、不良反应、美施康定的使用剂量变化。结果：两组治疗后FLIC量表评分较治疗前均有显著改善(P<0.01)，但治疗组较对照组提高更明显，具有显著性差异(P<0.01)；治疗组胃肠反应及神经系统反应有所好转，与对照组比较具有差异性(P<0.05)；两组美施康定用量及最大量比较有明显差异性。结论：仙龙定痛饮对骨转移癌痛患者具有确切疗效，该药能改善患者癌痛症状，提高患者的生存质量，减少吗啡类止痛药的临床使用剂量，从而相对减少其毒副反应，且未发生毒、副作用。 |
| English Summary: |
| to observe the clinical curative effect of Xianlong Dingtong Yin on osseous metastasis caused pain using random control studies.Methods:60 cases with Osseous Metastasis were randomly divided to treatment group(30 cases) to be treated with the drink and Morphine sulfate and control group(30 cases)to be treated with Morphine sulfate alone. When effective rates (CR+PR) reached 50%, changes of quality of life (PS rating, FLIC), side effects, dosage of Morphine sulfate were compared before and after treatment.Results:both groups significantly improved in FLIC (P<0.01), while the difference between them was significant (P<0.01); treatment group was significantly better than control group in gastrointestinal reaction and nervous system(P<0.05); conventional and maximum dosage of Morphine sulfate were significantly different.Conclusion:the drink has significant curative effects for osseous metastasis caused pain, improving quality of life, reducing dosage of morphine related drugs, in which side effects can be reduced. |
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