引用本文:俞小芬,薛盟举,郑烈.关节炎丸对大鼠佐剂性关节炎治疗作用的实验研究[J].世界中医药,2008,3(2):. |
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关节炎丸对大鼠佐剂性关节炎治疗作用的实验研究 |
Labotoray Study on Therapeutic Effect of Arthritis Pill on Rats with Adjuvant Arthritis |
投稿时间:2007-05-21 |
DOI: |
中文关键词: 类风湿性关节炎/中医药疗法 @ 关节炎丸 |
English Keywords:Rheumatoid Arthritis/ Chinese Medical Therapy @ the Arthritis Pill |
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中文摘要: |
目的:探讨关节炎丸治疗类风湿性关节炎的作用机制。方法:制作实验性关节炎(Adjuvant Arthritis,AA)大鼠动物模型,观察关节炎丸对大鼠血浆TNF-α及IL-1β影响,并与雷公藤阳性对照组进行比较。结果:关节炎丸组抑制炎症组织中TNF-α及IL-1β优于雷公藤组。结论:关节炎丸提高免疫通过影响炎症介质的释放而产生抗炎镇痛和抗风湿作用。 |
English Summary: |
to explore the action mechanism of Arthritis Pill for rheumatoid arthritis.Methods:Impact of the pill on TNF-α and IL-1β was observed on plasma of rats with adjuvant arthritis, and compared with positive control group which were treated with Tripterygii wilfordii Radix.Results:The pill was superior to the control medicinal in suppressing TNF-α and IL-1β of inflammatory tissue.Conclusion:Immunity Enhancement, anti-inflammatory and anti-rheumatism action of the Arthritis pill acts on arresting releasing of inflammatory mediators. |
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