引用本文:高 红 杨娟英 卢 露 郑伶俐 唐志书.益心解毒颗粒对动物心律失常的保护作用[J].世界中医药,2008,3(4):. |
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益心解毒颗粒对动物心律失常的保护作用 |
Protective Effect of Yixin Jiedu Granule on Arrhythmia in Lab Animal |
投稿时间:2008-04-22 |
DOI: |
中文关键词: 心律失常/中医药疗法 @ 益心解毒颗粒 |
English Keywords:Arrhythmia/Chinese Medical Therapy @ Yixin Jiedu Granule |
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中文摘要: |
目的:观察益心解毒颗粒对由CaCl2和乌头碱诱发动物心律失常的保护作用。方法:于大鼠末次用药60min后,舌下注射CaCl2和乌头碱诱发大鼠心律失常,观察大鼠心电图变化及心律失常情况。结果:益心解毒颗粒3g/kg可明显提高CaCl2致大鼠心律失常的存活率;益心解毒颗粒1.5~6.0g/kg可推迟乌头碱致大鼠心律失常的发生时间、缩短心律失常持续时间。结论:益心解毒颗粒对动物心律失常有明显的保护作用。 |
English Summary: |
to observe the protective effect of Yixin Jiedu Granule on arrhythmia in lab animals induced by CaCl2 and aconitine.Methods:60 minutes after last medication,CaCl2 and aconitine were sublingually injected to induce arrhythmia in rats whose conditions were measured by ECG.Results:The survival rate of rats intervened by CaCl2 was significantly improved at the dosage of 3g/kg; with a dosage of 1.5~6.0g/kg,onset of arrhythmia was delayed and duration shortened.Conclusion:Yixin Jiedu Granule has a remarkable protective effect on arrhythmia in lab animals. |
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