引用本文:陈雅静 文绍敦.酸脂清胶囊对尿酸盐结晶致急性痛风性关节炎IL-4的影响[J].世界中医药,2008,3(4):. |
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酸脂清胶囊对尿酸盐结晶致急性痛风性关节炎IL-4的影响 |
Effect of Suanzhiqing Capsule on Level of IL-4 in the Serum of Rat Model with Urate Crystal Caused Acute Gouty Arthritis |
投稿时间:2007-09-19 |
DOI: |
中文关键词: 急性痛风性关节炎/中医药疗法 @ 酸脂清胶囊 |
English Keywords:Acute Gouty Arthritis/ Chinese Medical Therapy @ Suanzhiqing Capsule |
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中文摘要: |
目的:观测酸脂清胶囊对急性痛风性关节炎大鼠模型血清中IL-4(白介素-4)表达的影响。方法:采用Coderre方法造模建立急性痛风性关节炎大鼠模型,造模后分别于3h、6h、9h取血,应用Elisa法测定IL-4的含量。结果:中药组的IL-4表达明显高于西药组及模型组(P<0.05)。结论:酸脂清胶囊能明显促进急性痛风性关节炎大鼠模型血清中IL-4的表达,对急性痛风性关节炎具有良好的治疗作用。 |
English Summary: |
Effect of Suanzhiqing Capsule on the Interleukin-4 (IL-4) level was observed. Methods:IL-4 Content was determined by Elisa method, in blood serum collected at 3-,6-,9-hour interval from acute gouty arthritis rat model established by the Coderre Method. Results:The IL-4 level of Chinese materia medica group was significantly higher than that of biomedicine group and of model group (P<0.05). Conclusions:with an obvious increase of IL-4 expression, Suanzhiqing Capsule showed satisfactory therapeutic effect for acute gouty arthritis. |
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