| 引用本文:陈文娜，李曦明，姜欣.中药脂康对高脂血症家兔免疫功能调节的实验研究[J].世界中医药,2008,3(6):. |
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| 中药脂康对高脂血症家兔免疫功能调节的实验研究 |
| Experimental Study of Zhikang Pill on Immune Regulation in Arteriosclerosis Rabbit |
| 投稿时间：2007-11-22 |
| DOI： |
| 中文关键词: 动脉粥样硬化 C反应蛋白 可溶性细胞间黏附分子-1 |
| English Keywords:Atherosclerosis C-reactive protein Soluble intercellular adhesion molecule-1 |
| 基金项目: |
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| 摘要点击次数: 1444 |
| 全文下载次数: 1642 |
| 中文摘要: |
| 目的：建立家兔高脂血症模型，探讨脂康方剂降低血脂、抑制动脉粥样硬化发展及调节机体免疫功能的机理。方法： 1）建立高脂血症家兔模型； 2）观察主动脉病理改变； 3）检测C反应蛋白、可溶性细胞间黏附分子-1的水平。结果： 1）成功建立高脂血症家兔模型； 2）通过对血脂水平、C反应蛋白、可溶性细胞间黏附分子-1水平的检测，发现脂康方剂可有效降低血脂水平，调节动脉粥样硬化家兔C反应蛋白、可溶性细胞间黏附分子-1的水平。结论：脂康方剂可有效降低高脂血症家兔血脂水平，并具有显著的抗炎作用。 |
| English Summary: |
| To explore the mechanism of immune-mediating of Zhikang Pill in decreasing blood lipid to control the development of atherosclerosis by setting up hyperlipemia models of New Zealand rabbits. Methods:1) Set up hyperlipemia models of New Zealand rabbits; 2) Observe the pathological changes in endarterium;3) Study the effects of Zhi Kang Pill by detecting the levels of C-reactive protein and soluble intercellular adhesion molecule-1 through ELISA. Results:1) Hyperlipidemia models were successfully established by using high-fat diet in New Zealand rabbits; 2) Zhi Kang Pill can effectively reduce blood lipid level and regulate the levels of C-reactive protein and soluble intercellular adhesion molecule-1.Conclusion:Zhi Kang Pill can effectively reduce the level of blood lipid in rabbit and has significant anti-inflammatory effects. |
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