| 引用本文:张大创，殷建明，罗陆一，张卫斌，黄梦雨，赵珊珊.通脉地仙丸对不稳定型心绞痛患者血清hs-CRP、Hcy的影响[J].世界中医药,2009,4(5):. |
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| 通脉地仙丸对不稳定型心绞痛患者血清hs-CRP、Hcy的影响 |
| Effect of Tongmai Dixian Pills on Serum hs-CRP and Hcy in Patients with Unstable Angina |
| 投稿时间：2008-11-05 |
| DOI： |
| 中文关键词: 不稳定型心绞痛/中医药疗法 @ 通脉地仙丸 超敏C反应蛋白 高同型半胱氨酸 |
| English Keywords:Unstable angina/ Chinese medical therapy @ Tongmai Dixian Pills Supersensitive C-reactive protein (hs-CRP) homocysteine (Hcy) |
| 基金项目: |
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| 中文摘要: |
| 目的：观察通脉地仙丸对不稳定型心绞痛(UA)患者血清超敏C反应蛋白(hs-CRP)、高同型半胱氨酸(Hcy)的影响。方法：将60例确诊UA肾阳亏虚证患者随机分组，治疗组30例，口服通脉地仙丸12g，3次/天，疗程30天；对照组30例，口服麝香保心丸，2次／粒，3次/天，疗程30天。治疗前后采集空腹静脉血，测定血清hs-CRP、Hcy水平。结果：2组治疗后血清hs-CRP、Hcy水平均显著降低(P<0.05、P<0.01)，其中治疗组hs-CRP水平低于对照组(P<0.05)。结论：通脉地仙丸具有抑制冠状动脉炎症反应作用，预防血栓形成，这可能是其治疗UA肾阳亏虚证的机理之一。 |
| English Summary: |
| To observe the effect of Tongmai Dixian Pills on supersensitive C-reactive protein (hs-CRP) and homocysteine (Hcy) in patients with unstable angina (UA).Methods:Sixty confirmed UA patients were allocated randomly to take orally Tongmai Dixian Pills (12g, 3 times a day), or Shexiang Baoxin Pills (2 pills, 3 times a day) for 30 days. Levels of hs-CRP and Hcy in venous blood from the patients’ empty stomach were determined before and after treatment.Results:When comparing post-treatment vs. prior-treatment, hs-CRP and Hcy levels in both groups were decreased significantly after treatment (P<0.05、P<0.01); and post-treatment hs-CRP level was lower in the treatment group than in the control group (P<0.05). Conclusion:Tongmai Dixian Pills can inhibit inflammatory reaction of coronary artery, prevent thrombosis, which may explain its mechanism to treat unstable angina with the pattern of kidney yang deficiency. |
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