| 引用本文:陈晓东.益气复脉注射剂治疗急性脑梗死41例疗效及其作用机制[J].世界中医药,2010,5(5):. |
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| 益气复脉注射剂治疗急性脑梗死41例疗效及其作用机制 |
| Efficacy and Mechanism of Yiqi Fumai Injection for Acute Cerebral Infarction |
| 投稿时间：2010-06-06 |
| DOI： |
| 中文关键词: 脑梗死/中医药疗法 @ 益气复脉注射剂 |
| English Keywords:Cerebral infarction/ Yiqi Fumai Injection |
| 基金项目: |
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| 中文摘要: |
| 目的：评价益气复脉注射剂治疗急性脑梗死的临床疗效及其可能的机制。方法：治疗组41例应用益气复脉注射剂，对照组58例应用丹参注射液治疗。治疗2周后对2组进行临床疗效、神经功能缺损评分(NFDS)、日常生活活动能力（Barthel）指数、血液流变学、血脂及血管内皮细胞功能进行比较。结果：总有效率治疗组为82.9%，对照组为70.7%，差别有显著性(P<0.05)。治疗后治疗组NFDS评分和Barthel指数、血浆纤维蛋白原含量、血脂各项指标、血清一氧化氮（NO）和内皮素（ET）含量与对照组比较有显著性改变(P<0.05或P<0.01)。用药后2组患者均未发现明显不适反应。结论：益气复脉注射剂可促进急性脑梗死患者神经缺损功能的恢复，改善患者的生活质量；机制可能与其改善患者血管内皮细胞功能、调节血脂和血液流变学等有关。 |
| English Summary: |
| To evaluate efficacy and mechanism of Yiqi Fumai Injection for acute cerebral infarction.Methods:Treatment group (n=41) was given Yiqi Fumai Injection, control group (n=51) given Danshen Injection. After 2-week treatment, comparison was made between two groups, i.e. efficacy, NFDS, Barthel index, hemorheology, lipids and function of vascular endothelial cells.Results:Total effective rate for treatment group= 82.9% compared with that of control group=70.7%, presenting significant difference (P<0.05). Neither group had obvious adverse effect.Conclusion:Yiqi Fumai Injection can stimulate recovery of neurologic defects, improve quality of life, which may be linked to improvement of function of vascular endothelial cells, regulation of lipid and hemorheology. |
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