| 引用本文:王亚平，史立华，顾江涛，张志银，朱艳，郑昕，庄敏之，张迪，武辉，周菲，郭兆玮，吴瑛，韩静，孙佳君，牛忆军.加味小陷胸汤干预湿热困脾型糖耐量受损30例临床研究[J].世界中医药,2010,5(5):. |
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| 加味小陷胸汤干预湿热困脾型糖耐量受损30例临床研究 |
| Clinical Research of Modified Minor Chest Bind Decoction on IGT of Pattern of Dampness-heat Accumulating Spleen |
| 投稿时间：2010-06-30 |
| DOI： |
| 中文关键词: 糖耐量受损/中医药疗法 加味小陷胸汤 湿热困脾 |
| English Keywords:Impaired glucose tolerance/ Chinese medical therapy Modified Minor Chest Bind Decoction dampness-heat accumulating spleen |
| 基金项目:上海市虹口区医学科研重大课题(0801-01) |
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| 中文摘要: |
| 目的：观察加味小陷胸汤干预湿热困脾型糖耐量受损，评价其疗效。方法：70例湿热困脾型糖耐量受损患者随机分为治疗组（n=33例）和对照组（n=37例），在生活方式干预的基础上，治疗组服加味小陷胸汤，对照组服二甲双胍片，观察治疗前后2组患者证候、血糖、胰岛素释放及其敏感性、胰岛素抵抗指数等改善情况。结果：治疗组患者在证候积分、血糖积分、胰岛素敏感性、体重指数、腰围、臀围与对照组比较有统计学意义。结论：加味小陷胸汤能显著改善患者中医临床症状，降低患者血糖积分，提高胰岛素敏感性，减轻体重，减小腰围，且无不良反应。 |
| English Summary: |
| To observe and evaluate the therapeutic effects of modified Minor Chest Bind Decoction on impaired glucose tolerance(IGT) in the pattern of dampness-heat accumulating spleen.Methods:60〖BP(〗（和中文摘要人数不一致）〖BP)〗patients of the abovementioned syndrome were randomized to treatment group (n=30) and control group (n=30), respectively treated with the decoction and metformin, besides life style intervention. Changes in syndromes, glucose, insulin releasing, insulin sensitivity, insulin resistance exponent were observed.Results:Treatment group was significantly different from control group in syndrome score, glucose score, insulin sensitivity, BMI, waist line, hip line.Conclusion:The decoction can significantly relieve the dampness-heat syndrome, lower glucose, enhance insulin sensitivity, reduce weight and waist line, while having little adverse reactions. |
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