| 引用本文:郭笑冬，张艳，林红伍，李玉叶，邵岩，丁怀莹，王士贤，李庆选.地肤叶水提物对四氧嘧啶致糖尿病小鼠降糖作用的观察[J].世界中医药,2011,6(3):. |
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| 地肤叶水提物对四氧嘧啶致糖尿病小鼠降糖作用的观察 |
| Impact of Difuye extract from Water on Alloxan-induced Diabetes Mice |
| 投稿时间：2010-03-08 |
| DOI： |
| 中文关键词: @ 地肤 糖尿病小鼠 降血糖 |
| English Keywords:Difu Diabetic mice Anti-diabetic |
| 基金项目:湖南省科学技术厅重大项目（2006SK2005） |
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| 摘要点击次数: 1074 |
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| 中文摘要: |
| 目的：探讨地肤叶水提物对糖尿病小鼠的降糖作用。方法：通过标准化四氧嘧啶造模糖尿病小鼠。选取血糖相近的小鼠分3组进行实验，分别喂药10天、10天、7天后观察实验组降糖结果，进行统计分析；并对实验小鼠进行毒理学实验。结果：地肤叶水提物剂量在4.0g/kg灌胃给药，7~10日均有一定降糖作用，与对照组比较可下降20%左右，最高达34.5%。结论：地肤叶水提物具有一定降糖作用，且不具有明显的毒副作用。 |
| English Summary: |
| To explore anti-diabetic effect of Difuye extract from water on diabetic mice model. Methods:Alloxan-induced diabetes mice with similar glucose values were selected, and given test extract for respectively 10 and 7 days, observed glucose values; carried out statistic analysis; and performed toxic experiment. Results:Anti-diabetic effect was shown after the extract was given 4.0g/kg intragastrically for 7-10 days, which was about 20% decrease, and 20% at most compared with glucose values of the control group. Conclusion: Difuye extract from water has definite anti-diabetic effect and no obvious side effects. |
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