To observe impact of Kang’ai Injection on life quality of cancer patient at late stage. Methods:Sixty patients were randomized to treatment group (n=30) using Kang’ai Injection plus chemotherapy, and control group (n=30) using chemotherapy alone. Observing parameters include Karnofsky scoring, weight changes, appetite and sleeping condition. Results:Total effective rates for treatment group and control group were 46.7% and 36.7% respectively (P>0.05); disease control rates were 86.7% and 76.7% (P>0.05). Appetite not affected by chemotherapy: treatment group 20 cases (66.7%), control group 13 cases (43.3%); sleeping improvement: treatment group 18 cases (60.0%)，control group 10 cases (33.3%)(P<0.05); Weight gained after treatment (P<0.05); Karnofsky scoring increased after treatment (P<0.05) and better than control group (P<0.05). Conclusion: Kang’ai Injection can enhance immunity of cancer patient at late stage, protect bone marrow, reduce reaction to chemotherapy, gain weight, raise life quality, and prolong survival time.