世界中医药
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引用本文:郭鑫,庞来祥,王玉香,程静.润肠通乐口服液对脾虚型便秘小鼠通便作用的实验研究[J].世界中医药,2011,6(5):.  
润肠通乐口服液对脾虚型便秘小鼠通便作用的实验研究
Pharmacology Research of Effect of Runchang Tongle Drink on Constipated Mice due to Spleen Deficiency
投稿时间:2010-08-06  
DOI:
中文关键词:  脾虚便秘  润肠通乐口服液
English Keywords:Constipation due to spleen deficiency  Runchang Tongle Drink
基金项目:
作者单位
郭鑫1,庞来祥2,王玉香2,程静2 1 陕西中医学院陕西省咸阳市世纪大道中段712046 2 解放军第451医院 
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中文摘要:
      目的:观察润肠通乐口服液对脾虚型便秘小鼠的通便作用。方法:采用隔日饮食+过度疲劳+缺水燥结法复制小鼠脾虚便秘模型,观察润肠通乐口服液对脾虚型小鼠首次排便粒数、脏器系数、游泳时间的影响。结果:润肠通乐口服液大、中剂量使小鼠排便粒数明显增多(P<0.05);大、中剂量可以明显提高小鼠游泳时间(P<0.05);大、中剂量组小鼠肝、脾、肾、胸腺系数较模型有明显提高(P<0.05)。结论:通过小鼠排便粒数、游泳时间以及脏器系数可知,润肠通乐口服液对脾虚型便秘具有良好的作用。
English Summary:
      To investigate effect of Runchang Tongle Drink on the constipated mice due to spleen deficiency. Methods:The mice model of constipation due to spleen deficiency was established by feeding every 2 days, fatigue and short of water. After taking Runchang Tongle Drink, the mice were observed for defecate amount, organ coefficient and swimming time. Results:In terms of the parameters assessed (defecate amount, organ coefficient and swimming time), high and medium dose of Runchang Tongle Drink can significantly relieve constipation symptoms (P<0.05). Conclusion: Concluded from our study, the Runchang Tongle Drink is effective to relieve constipation due to spleen deficiency.
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