To summarize the effectiveness and indication of operation on leg skin flap in combination with Chinese medicine for treatment of soft tissue loss of the foot dorsum. Methods:Thirty patients were treated with the operation in combination with Chinese medicine, area of skin flap ranged between (3cm×4cm) and (12cm×6cm). Results:All the transplanted skin flap survived, most of them restored sensation and had good appearance. Conclusion:Operation on leg skin flap in combination with Chinese medicine is a satisfactory treatment for soft tissue loss of the foot dorsum.