世界中医药
文章摘要
生脉饮合丹栀逍遥散加减治疗糖尿病后抑郁症44例临床研究
On Effectiveness of Shengmai Drink on top of Danzhi Xiaoyao Powder on Post Diabetes Depression in Forty-four Patients
投稿时间:2010-02-25  
DOI:
中文关键词: 糖尿病后抑郁症/中医药疗法  生脉饮合丹栀逍遥散
英文关键词: Shengmai Drink on top of Danzhi Xiaoyao Powder  Post diabetes depression/ Chinese medical therapy
基金项目:
作者单位
杜积慧,于文娟,于风云 烟台市中医医院内分泌科烟台市芝罘区幸福路39号264000 
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中文摘要:
      目的:探讨生脉饮合丹栀逍遥散治疗糖尿病后抑郁症的临床疗效。方法:86例辨证为气阴两虚、肝郁气滞的糖尿病后抑郁症患者随机分为2组,治疗组44例采用生脉饮合丹栀逍遥散加减治疗,对照组42例采用百忧解(盐酸氟西汀)治疗,疗程1个月。结果:治疗组44例中临床控制14例,显效17例,有效8例,无效5例,总有效率88.6%;对照组42例中临床控制9例,显效15例,有效9例,无效9例,总有效率78.6%。2组比较有统计学意义(P<0.01),治疗组明显优于对照组;治疗组治疗后SDS评分、HAMD评分亦明显优于对照组(P<0.01),治疗组无不良反应发生。结论:生脉饮合丹栀逍遥散加减治疗糖尿病后抑郁症是有效且安全的。
英文摘要:
      To investigate effectiveness of Shengmai Drink on top of Danzhi Xiaoyao Powder on post diabetes depression. Methods:Ninety patients identified as qi-yin dual insufficiency and liver-depression qi stagnation were randomized. The treatment group was treated with Shengmai Drink on top of Danzhi Xiaoyao Powder with Prozac as control for a course of 1 month. Results:The total effective rate of treatment group was 88.6%, 14 patients had the conditions under controlled, 17 patients were significantly effective, 8 patients were effective, 5 patients didn’t quite respond to the treatment. The total effective rate of control group was 78.6%, 9 patients had their conditions under controlled, 15 patients were significantly effective, 9 patients were effective, 9 patients didn’t quite respond to the treatment. The treatment group had statistically better effectiveness (P<0.01), higher SDS and HAMD scores (P<0.01), without adverse event reported. Conclusion:Shengmai Drink on top of Danzhi Xiaoyao Powder is effective and safe for treatment of post diabetes depression.
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