| To evaluate impact of Yuzhuqing Granules, formulated according to the therapeutic methods of turbid stasis-resolving, liver kidney nourishing, on sexual function of female hypertension patients.Methods:Sixty patients were randomized according to digit table to treatment group (n=28, Nifedipine 30mg/d plus Metroprolol succinate 25mg，bid plus Yuzhuqing Granules 1package，tid.) and control group (n=29 Nifedipine 30mg/d plus Metroprolol succinate 25mg，bid）, changes of blood pressure , sexual function and patient safety were observed.Methods:The total effective rate of the treatment group was 85.71%, compared to 82.76% that of the control group (P>0.05); sexual index and sexual intercourse satisfaction were significantly different in the treatment group prior to and after treatment (P<0.01), so was sexual arousal index (P<0.05); Compared with the following index of the control group, sexual index, sexual arousal index, sexual intercourse satisfaction index, orgasm index were significantly different (P<0.05，P<0.01); Both groups had increased estradiol level and decreased ketone level after treatment(P<0.05); Compared with the index of the control group, the treatment group has higher estradiol level and lower ketone level (P<0.01).Conclusion:In addition to confirmed efficacy for hypertension, Yuzhuqing Granules can improve sexual function in female hypertension patients, and improve life quality of the patients. |
