| 引用本文:宋明福，王安桥，朱国龙，刘敏.“生血二号”治疗特发性血小板减少性紫癜对巨核细胞影响的实验研究[J].世界中医药,2012,7(2):. |
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| “生血二号”治疗特发性血小板减少性紫癜对巨核细胞影响的实验研究 |
| Impact of ShengxueⅡ on Megalocaryocyte in Mice with Idiopathic Thrombocytopenic Purpura |
| 投稿时间：2011-11-14 |
| DOI： |
| 中文关键词: 血小板减少性紫癜/中医药疗法 巨核细胞 @ 生血二号 |
| English Keywords:Idiopathic thrombocytopenic purpura/ Chinese medical therapy Megalocaryocyte @ ShengxueⅡ |
| 基金项目: |
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| 摘要点击次数: 1757 |
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| 中文摘要: |
| 目的：观察“生血二号”对ITP治疗前后的骨髓巨核细胞的影响。方法：选择血小板减少小鼠共30只，雌雄兼用，分为中药组及激素组，治疗15天后，查骨髓产板巨核细胞数。结果：经小鼠实验表明：中药组和激素组与模型组比较有统计学意义（P<0.01）；中药组和激素组与正常组比较无统计学意义（P>0.05）；中药组与激素组比较无统计学意义（P>0.05）。结论：“生血二号”能促进巨核细胞向成熟分化，促进血小板生成，说明中药在治疗慢性血小板减少性紫癜较激素安全可靠，疗效显著。 |
| English Summary: |
| To observe the impact of ShengxueⅡ on megalocaryocyte in bone marrow in mice with idiopathic thrombocytopenic purpura (ITP).Methods:Thirty male and female mice with thrombocytopenia were treated by Chinese medicine, or by hormone respectively for 15 days, and megalocaryocyte in bone marrow were counted.Results:Either the medicine group or hormone group had significant differences when comparing with the model group (P<0.01); but without significant differences when comparing with the normal group (P>0.05); There was no significant different between the medicine group and hormone group (P>0.05).Conclusion:ShengxueⅡcan promote megalocaryocyte differentiation and produce blood platelet, indicating it is a safer and more effective treatment than hormone for the treatment of idiopathic thrombocytopenic purpura. |
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