| 引用本文:夏乐敏，王运律，胡琦，孙思明.慢性再障中医证型与多个因素相关性研究[J].世界中医药,2012,7(3):. |
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| 慢性再障中医证型与多个因素相关性研究 |
| Correlation Analysis between Multiple Factors and TCM Syndromes of Chronic Aplastic Anemia |
| 投稿时间：2010-09-02 |
| DOI： |
| 中文关键词: 慢性再生障碍性贫血/中医证型 |
| English Keywords:Chronic aplastic anemia/TCM syndromes |
| 基金项目: |
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| 摘要点击次数: 1287 |
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| 中文摘要: |
| 目的：探讨免疫、内分泌系统多个指标与慢性再生障碍性贫血(CAA)中医辨证分型的关系并应用统计学判别分析方法，建立CAA的中医证型判别方程。方法:对77例CAA患者进行辨证分型，分为肾阳虚型、肾阴虚型、肾阴阳两虚型3组，且与20名健康人作对照，并行免疫、内分泌系统的多个指标的实验室检查。以判别分析方法建立CAA辨证分型的判别方程，对中医证型进行客观量化。结果： 1)77例CAA患者中，CD3、CD4、CD8、CD3+28+、C3、C4、IgA、FT4在3组中存在不同程度差异。 2)应用判别分析方法建立了CAA中医证型判别方程，筛选出与辨证分型最相关的Hb（g/L）、PLT（×109/L）、CD55（%）、CD8（%）、CD+3CD+95(%)、IgA（g/l）、C3（g/l）、C4（g/l）、FT4（ng/dl）等9个免疫学、内分泌指标。结论：CD3、CD4、CD8、CD3+28+、C3、C4、IgA、FT4等指标可能作为CAA临床辨证分型的客观依据。而应用判别分析方法建立了CAA中医证型判别方程，使CAA辨证分型得以客观量化，具有临床实际意义。 |
| English Summary: |
| To discuss the relationship between various endocrine or immunological factors and TCM syndromes of chronic aplastic anemia(CAA), and to establish an equation to determine TCM syndromes.Methods:77 CAA patients were divided to kidney-yang deficiency group, kidney-yin deficiency group and kidney-yin-yang-deficiency group.Endocrine or immunological parameters of the patients were assessed and compared with 20 healthy volunteers, in order to establish an equation to identify their TCM syndromes, and to analyze the correlations.Results: 1) CD3, CD4, CD8, CD3+28+, C3, C4, IgA, FT4 have different levels in three CAA groups. 2) Absolute value of Hb(g/L), PLT(×109/L), CD55(%), CD8(%), CD+3CD+95(%), IgA(g/l), C3(g/l), C4(g/l), FT4(ng/dl) were selected to form a discriminatory formulas.Conclusion:CD3, CD4, CD8, CD3+28+, C3, C4, IgG, FT4 can be the indicators suggestive of TCM syndromes of CAA in clinical practice.The establishment of the equation for syndrome differentiation is objective, quantitative and clinically meaningful. |
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