| 引用本文:田 静 曹 靖 周晓琳 何周康.良附胃漂浮片的制备及体外溶出度的研究[J].世界中医药,2012,7(6):. |
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| 良附胃漂浮片的制备及体外溶出度的研究 |
| Preparation and in vitro Dissolubility of Liangfu Gastric Floadting Tablets |
| 投稿时间：2012-04-23 |
| DOI： |
| 中文关键词: 良附胃漂浮片 漂浮和释药 |
| English Keywords:Liangfu stomach floating tablets Floating and release |
| 基金项目: |
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| 中文摘要: |
| 目的：研究良附胃漂浮片的处方，片剂的制备工艺和体外溶出度。方法：采用正交设计以羟丙基甲基纤维素（HPMC）、十六醇、碳酸氢钠、羧甲基淀粉钠（CMC-Na）为辅料，压片即得。并考察其体外溶出度及漂浮度。结果：漂浮片的迟滞时间小于5min，持续漂浮时间都大于12h，12h的累积释药量大于90％。结论：研制的良附胃漂浮片具有较好的漂浮特性和释药特性。 |
| English Summary: |
| To investigate prescription, preparation process and in vitro release of Liangfu stomach floating tablets. Methods: The orthogonal design was used to determine the formulation containing the fiber （HPMC） and sixteenth alcohol, sodium carbonate hydrogen, the sodium starch sodium （CMC-Na） as adjuvant material, and in vitro release of and floating was tested. Results: The delay time was less than 5min, floating time was more than 12h, 12h of dose release reached more than 90 %. Conclusion: The Liangfu stomach floating tablets have good floating and release characteristics. |
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