世界中医药

目的：观察半夏泻心汤治疗三联未根除HP感染者的治疗作用。方法：随机将我院就诊的三联未根除HP感染者100例分为2组，治疗组50例，对照组50例，治疗组服用半夏泻心汤加减治疗，对照组口服吗丁啉+得必泰治疗，2组均服药4周，停药随访4周后，评价半夏泻心汤的HP根治率、疗效和安全性。结果：治疗组HP根治率为84.0%，对照组HP根治率为54.0%，2组HP根治率比较差异有统计学意义（P<0.05），治疗组HP根治率高于对照组；治疗组治愈率为80.0%，对照组治愈率为48.0%。2组治愈率比较差异有统计学意义（P<0.05），治疗组有效率为96.0%，对照组有效率为74.0%，2组有效率比较差异有统计学意义（P<0.05），治疗组的治愈率和有效率均明显高于对照组。2组安全性比较差异有统计学意义（P<0.05），治疗组安全性优于对照组。结论：半夏泻心汤治疗三联未根除HP感染者在HP根治率和疗效方面均优于吗丁啉+得必泰，且安全性较高。

English Summary:

To observe the therapeutic effect of Banxia Xiexin Decoction HP infected patients failed in triple eradication therapy.Methods:A total of 100 patients failed in thriple eradication therapy were selected and randomly divided into two groups in our hospital.Control group（n=50）were treated with Domperidone and Compound Bismuth Aluminate Granules，meanwhile observation group (n=50)were treated with Banxia Xiexin Decoction.The patients of the two groups were treated for four weeks，after it，followed up for four weeks.At last，HP radical rate，efficacy and safety of Banxia Xiexin Decoction HP were evaluated in the end of the observation. Results:HP radical rate of the two groups respectively was 84.0% and 54.0%，the rate of treatment group was higher than control group with Statistical analysis (P<0.05)，the cure rate of the two groups respectively was 80.0% and 48.0%，while the effective rate respectively was 96.0% and 74.0%，then we can see obviously，both of the cure rate and the effective rate of treatment group were predominantly higher than that of the control group (P<0.05).The security of two groups had significant difference (P<0.05)，the observation group was better than the control group in safety.Conclusion:Banxia Xiexin Decoction applied to triple radical gastric HP failure patient was better than Domperidone and Compound Bismuth Aluminate Granules in HP radical rate，cure rate and the effective rate，and which was more safety.

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