世界中医药
文章摘要
引用本文:卢红蓉 杜 松.重型手足口病病机探讨[J].世界中医药,2013,8(2):.  
重型手足口病病机探讨
Study on Pathogenesis of Severe Hand-foot-mouth Disease
投稿时间:2012-11-05  
DOI:10.3969/j.issn.1673-7202.2013.02.016
中文关键词:  手足口病  重症  病机
English Keywords:Hand-foot-mouth disease  Severe symptoms  Pathogenesis
基金项目:基金项目:国家中医药管理局2009年度行业专项课题“中医药防治甲型H1N1流感、手足口病及流行性乙型脑炎的诊疗规律与机制研究(编号:200907001-4)
作者单位
卢红蓉 杜 松 中国中医科学院中医基础理论研究所北京100700 
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中文摘要:
      手足口病属于中医温病中“温疫”范畴,由温热挟湿疫毒感染所致。重症手足口病多由普通型发展而来,病位在肺、脾、心、肝,发病符合中医温病的发展规律,初起以肺卫为主,可见卫气分证,极期入营血,内陷心肝,热入心包,肝热动风则见高热、神昏、抽搐、颈项强直等危象;疫毒入里犯及心肺,肺失宣降,水气停滞,水气上凌心肺则见心悸、咳频气急、鼻翼煽动、口唇发绀、张口抬肩、呼吸节律改变;热邪灼伤肺络,血溢脉外,或疫毒热邪耗气伤阴,心肺气脱,气不摄血则见咳吐口吐白色或粉红色泡沫痰;疫毒热邪耗气伤阴,日久及阳,心阳外脱,则见身热、神昏或突然面色苍白、大汗淋漓、四肢逆冷等内闭外脱危候。
English Summary:
      Hand-foot-mouth disease belongs to the category of “pestilence ”of epidemic febrile disease of TCM, caused by the warm-wet disease virus infection. Severe hand-foot-mouth disease develops from the common type, locating in lung, spleen, and heart, liver, following the defensive-qi-nutrient-blood development principle of TCM. It begins with lung Wei, and develops to qifen period,then moves to yin and blood period in critical period when heat evil invaginates liver and pericardium, and intense heat generates wind, then symptoms of high fever, clouded spirit, seizure, rigidity of the neck and nape would been seen; if heat evil invaginates heart and lung,the lungs would lose its clearing action,then fluid stops in the body and attacks the heart, then symptoms of palpitation, frequent coughing and rapid breathing, lip cyanosis, change of breath rhythms would be seen; if pathogenic heat burns pulmonary vessels, then blood overflows to outside of pulse, or Qi –yin is damaged by pathogenic heat, and Qi fails to control blood, the symptoms of cough, spitting white or pink frothy sputum will be observed; if disease develops and damages yang, then severe and critical syndrome as internal obstruction and external collapse will be seen including symptoms of high fever, clouded spirit, pale expression, severe sweating, counterflow cold of the limbs.
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