| 引用本文:朱路平 赵宜红 孙曼 杨景华 周甜 赵新年 张雁冰 李寅超.阿胶补血软胶囊对小鼠失血性贫血的影响[J].世界中医药,2013,8(04):. |
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| 阿胶补血软胶囊对小鼠失血性贫血的影响 |
| Effect of Ejiao Soft Capsule on Hemorrhagic Anemia in Mice |
| 投稿时间：2012-11-21 |
| DOI： |
| 中文关键词: 失血性贫血/中医药疗法 阿胶补血软胶囊 红细胞 血红蛋白 |
| English Keywords:Hemorrhagic anemia/ Chinese medical therapy Ejiao soft capsules Erythrocytes Hemoglobin |
| 基金项目: |
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| 中文摘要: |
| 目的：观察阿胶补血软胶囊对小鼠失血性贫血的影响。方法：采用小鼠眼底后静脉丛放血法，造成失血性贫血动物模型，观察给药后各组小鼠红细胞(RBC)和血红蛋白(Hb)和游泳时间，并用ELISA方法测定血清中促红细胞生成素(Erythropoietin，EPO)。结果：小鼠造成失血性贫血模型以后，体能明显下降，负重游泳时间缩短，RBC数目和Hb含量明显降低，EPO反馈性相对增加。阿胶补血软胶囊在提高动物体能的同时，其RBC和Hb异常明显改善，并可使血清EPO进一步升高。结论：本实验条件下，阿胶补血软胶囊具有抗贫血功能，能提高小鼠的体力，增加失血性贫血小鼠的RBC数目和Hb含量，这些作用可能与其增加血中EPO含量有关。 |
| English Summary: |
| To observe the effect of Ejiao soft capsule on anemia in mice.Methods:The mice were given fundus venous plexus phlebotomy to cause hemorrhagic anemia in animal models. The red blood cell (RBC), hemoglobin (Hb) and swimming time were observed after administration of the medicine, erythropoietin (EPO)in serum was measured by ELISA.Results:After triggering the hemorrhagic anemia model, the physical efficiency of the mice decreased, their swimming time reduced, RBC number and Hb dropped significantly, and EPO feedback relatively increased. Ejiao soft capsules strengthened animals' physical efficiency, improved abnormality of RBC and Hb, and EPO in serum were further increased.Conclusion:In this experimental condition, Ejiao soft capsule possesses anti-anemia function, it can improve the physical strength of the mice, increase RBC number and Hb content of the hemorrhagic anemia mice. These effects may be related to the increase of EPO levels in serum. |
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