Abstract:To Observe the influential mechanism of Bufei Yishen decoction on sperm motion parameters. Methods: Ninety male patients diagnosed as infertility in Chinese medicine outpatient were randomized into treatment group and control group. Patients in treatment group were given Bushen Yifei decoction, 150 ml per time, 2 times a day; patients in control group took oral administration of VE capsules, 50 mg per times, 3 times a day. The treatment course were both 1 month, and semen analysis were made before and after treatment. Results: Bushen Yifen decoction could significantly improve the percentage of A level sperm, the linear speed of sperm, anterograde effect, and linearity (P<0.01). Conclusion:: Bufei Yishen decoction can significantly improve sperm motility parameters.