This was a clinical observation on chronic obstructive pulmonary disease (COPD) patients in the tranquilization period treated by Moxa Cone Moxibustion and western medicine. Methods: 108 COPD patients in the tranquilization period recruited were randomized and given basic western medical treatment. The treatment group (53 cases) received Moxa Cone Moxibustion on back shu points for 4 weeks. Results: Both groups improved life quality after treatment， and the treatment group had better outcome with regard to relieving cough and heavy breathing， higher score assessing quality of life， and reducing frequency of acute exacerbation (P<0.05). Conclusion: Integrated treatment of Moxa Cone Moxibustion and Western medicine can improve the quality of life and reduce frequency of acute exacerbation.