“Kidney Yang Deficiency syndrome” (KYDS) and “Abnormal Savada syndrome” (ASS) are, respectively, typical syndromes in Traditional Chinese medicine (TCM) and Traditional Uighur medicine (TUM). Many studies have been carried out in order to explore the material basis of these two syndromes. These studies find that there are similarities and differences between the material basis of KYDS and ASS. However, comparison of these two syndromes was rarely reported. Asthma is a chronic inflammatory disorder of the airways, caused by Kidney Yang Deficiency or potential Kidney Yang Deficiency in TCM and Abnormal Savada in TUM. But there is few research to compare asthma with KYDS and ASS. Based on the literature review and preliminary research by our team, this article probes the similarities and differences between the scientific basis of KYDS, ASS and models of combining these two syndromes with asthma. By comparing analogous syndromes across traditional medicines, it helps us with a better understanding of both traditional medicines and establishing a holistic medical framework in the future.