“Syndrome” and “Treating different diseases with same method”, which are important concepts in Traditional Chinese Medicine (TCM), have profound meanings and are widely used in clinical practice. Chronic inflammatory diseases such as asthma, chronic obstructive pulmonary disease and atopic dermatitis have some similarities in terms of pathogenesis and intervention methods. However, current treatments for these diseases have limitations. According to the theory of TCM, these diseases are usually identified as syndrome “Kidney deficiency” or “Qi deficiency”, therefore, treated with the method “strengthening Kidney and replenishing Qi”. This is in line with the thought of “Use similar method to treat different diseases as identical syndrome”. Strengthening Kidney and replenishing Qi is proved to be effective treatment, based on our preliminary work, this is because strengthening kidney have an impact on HPAA and replenishing Qi on immunity system, and correct abnormal relations. The research proved a synergistic effect between strengthening Shen and replenishing Qi herbs.