To observe the clinical efficacy of Qingrequtan decoction treating acute exacerbations of chronic obstructive pulmonary disease (AECOPD) among aged people. Methods: One hundred and twenty AECOPD patients admitted to Respiratory Department of our hospital were selected and randomly divided into observation group (n=60) and control group (n=60) using a random number table. Patients in both groups were given conventional treatment, including antibiotics, bronchodilators, oxygen, and other treatment in light of symptoms. Patients in observation group received extra treatment of modified Qingrequtan decoction, one dosage a day, divided into two parts for morning administration and evening administration. One treatment course consisted of 14 continuous days of treatment, and clinical efficacy were compared. Results: After a course of treatment, the total effective rate in observation group was significantly higher than that in the control group (χ2=10.457,P<0.01),with statistical significance. There were no significant differences between the two groups in terms of symptoms, sign score, FEV1% and FEV1/FVC and dyspnea index of the patients before the treatment (P>0.05). There were obvious improvement of the indexes after treatment in both groups, and the observation group showed better improvement compared with the control group (P<0.01). Conclusion: Qingrequtan decoction treating acute exacerbations of chronic obstructive pulmonary disease (AECOPD) among aged people shows satisfactory therapeutic effect in improving clinical symptoms, signs and pulmonary function, which is worth generalizing.