Body constitution reflects the characteristics of whole human body, therefore, it is only appropriate to understand and research human physiology and pathology through a holistic approach. The surging study on constitutional medicine owes its origin to the concept of holism in Traditional Medicine. Compared to other country’s traditional medicines, Traditional Chinese Medicine (TCM) takes all factors into accounts in order to achieve effective treatment. Therefore, today’s constitutional medicine should lay its cornerstone on the system of diagnosis and treatment according to syndromes in TCM. Applying modern scientific methods to develop the body constitution medicine primarily focuses on the following directions: 1) further distinguishing basic types of body constitution; 2) introducing objective indicators in the identification process of body constitution; 3) study on the composite body constitution which is composed from the basic body constitutions and their control methods; 4) establishing a model that can be used for identifying body constitution of human body by combining the discriminant based on qualitative rules and choice based on quantitative calculation; 5) establishing a Computer Simulation Platform that can be used to describe the functional activity of the human body, to verify the model of the human body, and to identify the human body constitution.