世界中医药

作者	单位
杨佳1 赵百孝1 韩丽1 刘平1 王磊1 白桦1 黄剑1 刘钧天1 朱茂祥2 杨陟华2	1 北京中医药大学针灸推拿学院，北京，100029； 2 中国人民解放军军事医学科学院，北京，100071

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中文摘要:

目的：观察不同浓度艾烟对大鼠血液微循环的影响，为临床安全使用艾烟提供参考。方法：将168只wistar大鼠随机分为四组，每组42只分别暴露于0%、10%、40%、70%浓度（以染毒柜不透光率度量），每天20 min，26周后取材，ELISA法检测不同浓度组大鼠血清中vWF、ox-LDL的含量。结果：vWF含量随艾烟浓度升高而逐渐下降，低、中、高浓度组vWF含量与空白对照组相比均有统计学意义；中浓度组艾烟干预后，血清中ox-LDL含量显著性升高，其余各组ox-LDL含量与空白组相比无统计学意义。结论：1）艾烟可使血小板聚集程度下降，提示艾烟可能具有改善微循环，从而促进机体新陈代谢的作用。2）低浓度艾烟对血管内皮未见明显损伤。

English Summary:

To observe the effect of moxa somke with different concentrations on blood microcirculation and provide reference on security of moxa smoke in clinic. Methods: A total of 168 rats were randomly divided into 4 groups ，42 in each group. Rats in control group， low concentration goup， medium concentration group， high concentration group were respectively exposed to moxa smoke of 0%， 10%， 40%， 70% concentration (in terms of opacity) for 20 min each day ， after 26 weeks rats were executed and drawn materials and with ELISA method ox-LDL、vWF in rats blood serum of different group were tested. Results: vWF showed downtrend as the concentration of moxa smoke ascended， which of low， medium， high concenteation group significantly declined compared with control group; It has significantly rise in medium cencentrtion group compared with control group，the rest groups had no significant change by contrast with control group. Conclusion: 1) The rise of concentration of moxa smoke brings down Platelet aggregation，promotes body metabolism and improves microcirculation. 2) Low concentration of moxa smoke indicates no injury on vascular endothelial.

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