The incidence rate of refractory acute leukemia (RAL) gets higher year by year. At present， the main treatment for the disease are still hematopoietic stem cell transplantation， molecular targeted therapy， new drug development and new methods such as chemotherapy regimens. The main symptoms of the disease are anaemia， bleeding， infection and lymphadenectasis in spleen and liver. The disease causes depletion of organs which leads to weakness of the whole body and final death. TCM brings the disease into “consumptive disease” category. Different syndrome types are summed up according to different clinical symptoms.