Under the guidance of TCM theory of evidence-based medicine, explore clinical efficacy of Yin-nourishing, qi-reversing method in patients with chronic obstructive pulmonary disease.Methods:A total of 106 patients of chronic obstructive pulmonary disease were divided into the control group (treated with conventional western medications such as oxygen, anti-infection meds, anti-spasmolysis and anti-asthma meds, meds for reduce cough phlegm and dilate bronchi); treatment group were treated with TCM decoction of Yin-nourishing, qi-reversing effect, in addition to conventional western medicine treatment. After a treatment course of 14 days, clinical efficacy was evaluated. Results: Symptoms (cough, sputum color and breathing, chest tightness,heart function change, white blood cells and neutrophils) improved significantly in treatment group than the control group (P<0.05). Conclusion: The clinical observation showed that Yin-nourishing, qi-reversing method can promote improvement of clinical symptoms of chronic obstructive pulmonary disease, therefore provide new method and thoughts for COPD treatment.