世界中医药
文章摘要
引用本文:杨佳妹1,2 韩路拓1,2 任钧国2 李军梅2 李鸿海2.中医治疗肝癌常用中药用药规律的文献分析[J].世界中医药,2013,8(10):.  
中医治疗肝癌常用中药用药规律的文献分析
Literature Analysis of Traditional Chinese Medicine Commonly used for Treatment of Liver Cancer
投稿时间:2013-09-12  
DOI:10.3969/j.issn.1673-7202.2013.10.006
中文关键词:  肝癌  中药  中医  用药规律
English Keywords:Liver cancer  Traditional Chinese medicine  Medication rules
基金项目:科技部十二五重大新药创制课题(编号:2012ZX09301002-004)
作者单位
杨佳妹1,2 韩路拓1,2 任钧国2 李军梅2 李鸿海2 1 北京中医药大学北京100029 2 中国中医科学院西苑医院基础医学研究所北京市中药药理重点实验室北京100091) 
摘要点击次数: 1354
全文下载次数: 2917
中文摘要:
      目的:探讨中药治疗肝癌的用药规律,为肝癌临床治疗及新药研发提供参考。方法:搜集2002-2012年公开发表的中文临床与实验研究文献,运用频数统计法进行统计分析。结果:临床文献中所用中药频次由高到低的是白术,黄芪,茯苓,柴胡,甘草等;实验研究文献所用中药频次由高到低的是黄芪,半枝莲,白花蛇舌草,甘草,茯苓等。临床用药两两配伍的频次由高到低是白术配伍茯苓、白术配伍黄芪、黄芪配伍党参、黄芪配伍当归、黄芪配伍茯苓等。常用药物类别主要为补虚药,其他常用类别为清热解毒药、活血化瘀药、理气药、利水渗湿药、消食药等。结论:治疗肝癌中医用药有一定的规律,主要以补虚药为主,配伍清热解毒、活血化瘀药,同时结合辨证的具体情况配伍其他类别的中药。
English Summary:
      To investigate the medication rule of traditional Chinese medicine for treatment of liver cancer. Methods: Database of scientific papers published between 2002-2012 on TCM treatment of liver cancer was set up and analyzed by Frequency method. Results: The herbs mostly common used in clinical practice are Rhizoma Atractylodis Macrocephalae, Astragalus membranaceus, Poria cocos, Radix bupleuri, Liquorice. The single medicine mostly commonly experimented in labs are Macrocephalae, Sculellaria barbata, Oldenlandia diffusa, Liquorice, Poria cocos. The commonly used medicine pairs are Rhizoma Atractylodis Macrocephalae with Poria cocos, Rhizoma Atractylodis Macrocephalae with Astragalus membranaceus, Astragalus membranaceus with Pilosulae, Astragalus membranaceus with Angelica sinensis, Astragalus membranaceus with Poria cocos. These herbal medicines are used mainly for tonifying Qi, or for clearing heat antitoxicant, or promoting blood-activating and removing stasis, or regulating qi, diuresis or diffusing dampness, digestion. Conclusion: There are certain prescription rules when treating liver cancer with TCM: Most commonly used medicine is tonifying medicine, in combination with heat-clearing antitoxicant medicine and blood-activating medicine. Based on result of syndrome differentiation, other categories of Chinese traditional medicine can be used.
查看全文  查看/发表评论  下载PDF阅读器