世界中医药
文章摘要
引用本文:陈丽萍1 陈 岩2 董 艳3.大承气汤对大肠杆菌体外抑菌作用的研究[J].世界中医药,2013,8(10):.  
大承气汤对大肠杆菌体外抑菌作用的研究
Studies on the Effect of Dahuang Chengqi Decoction on the Antibacterial Effect of Escherichia Coli in Vitro
投稿时间:2013-03-31  
DOI:10.3969/j.issn.1673-7202.2013.10.033
中文关键词:  大承气汤  大肠杆菌  抑菌作用
English Keywords:Dahuang Chengqi decoction  Escherichia coli  Antibacterial effect
基金项目:
作者单位
陈丽萍1 陈 岩2 董 艳3 1 黑龙江省牡丹江市第一人民医院检验科,牡丹江,157009
2 黑龙江省医院感染内科,牡丹江,150036
3 牡丹江医学院微生物免疫教研室,牡丹江,157011) 
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中文摘要:
      目的:研究大承气汤对大肠杆菌的体外抑菌作用,以探讨中药大承气汤的临床应用价值。方法:将大肠杆菌涂布于培养基表面培养,然后加大承气汤,同时以头孢拉啶作为阴性对照,记录抑菌圈直径,比较两组药物的应用对大肠杆菌体外抑菌的作用。结果:大承气汤对大肠杆菌有一定的抑菌作用,抑菌圈直径高达13.9 mm,为中度敏感;先锋霉素6号对大肠杆菌的抑菌作用非常强,抑菌圈直径高达19.1 mm,为高度敏感。结论:大承气汤对大肠杆菌有良好的体外抑菌作用,可加强进一步临床研究,应用于临床轻度大肠杆菌感染者的治疗。
English Summary:
      To study the effect of Dahuang Chengqi Decoction on escherichia coli in vitro in order to explore clinical application value of Dahuang Chengqi Decoction. Methods:Coat escherichia coli in medium surface culture and add Dahuang Chengqi Decoction. Take both spore and chemoprotective as negative control, record bacteriostatic circle diameter, compare two groups of drug application on escherichia coli in vitro antibacterial effect. Results: Dahuang Chengqi decoction has a certain effect on escherichia coli, bacteriostatic circle diameter went up to 13.9mm which is considered moderately sensitive; Cephalosporin #6 has a strong effect on the antibacterial effect of escherichia coli, bacteriostatic circle diameter went up to 19.1mm, which is highly sensitive. Conclusion: Dahuang Chengqi decoction has good antibacterial effect on escherichia coli in vitro. Further clinical studies can be carried out to apply the decoction to the clinical treatment of mild escherichia coli infections.
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