世界中医药

作者	单位
李素红1 魏海燕2 李晓燕3 黄冬霞4	1 河北省邯郸明仁医院中医内科，邯郸，056001 2 河北邯郸县医院内分泌科，邯郸，056006 3 邯郸市中心医院消化内科，邯郸，056014 4 河北省邯郸市中医院中医内科，邯郸，056002

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中文摘要:

目的:观察小建中汤加味对脾胃虚寒型消化性溃疡的临床疗效。方法:将136例符合条件的脾胃虚寒型消化性溃疡患者随机分为2组，每组68例，对照组给予常规西医治疗，治疗组给予小建中汤加味治疗，疗程均为4周。结果:治疗总有效率方面，对照组(70.59%)和治疗组患者(91.18%)比较的差异具有统计学意义(χ2=5.1271，P＝0.023);中医证候积分改善情况比较，治疗组(91.18%)与对照组(72.05%)，比较的差异具有统计学意义(χ2=5.1434，P＝0.023<0.05);1年后复发率比较，治疗组(12.34%)低于对照组(42.31%)，且比较的差异有统计学意义。结论:小建中汤加味可有效治疗脾胃虚寒型消化性溃疡，有效改善中医证候，降低复发率。

English Summary:

To observe the clinical curative effect of modified Xiaojianzhong Decoction treating peptic ulcer of the spleen-stomach deficiency cold type. Methods: One hundred and thirty six patients who met the criteria of peptic ulcer of the spleen-stomach deficiency cold type were randomly divided into treatment group (n=68) and control group (n=68). Patients in the control group were given the conventional Western medicine treatment, and patients in the treatment group received modified Xiaojianzhong decoction. The courses of treatment were both 4 weeks. Results: The total effective rates in control group and treatment group were respectively 70.59% and 91.18%, which showed statistically significant difference (χ2= 5.1271, P=0.023); as for improvement of TCM syndrome score assessment, there was significant difference between the treatment group (91.18%) and control group(72.05%), (χ2=5.1434,P=0.023<0.05); the relapse rate of one year after treatment in the treatment group was 12.34%, which was significantly lower than the 42.31% of the control group. Conclusion: Modified Xiaojianzhong decoction could effectively cure peptic ulcer of the spleen-stomach deficiency cold type, improve TCM syndromes, and reduce the relapse rate.

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