引用本文:郭 明 高铸烨 王培利 史大卓.中药防治血脂异常进展[J].世界中医药,2013,8(12):. |
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中药防治血脂异常进展 |
A Review of Chinese Medicine Herbs and Formulas for Treating Dyslipidemia |
投稿时间:2013-11-07 |
DOI:10.3969/j.issn.1673-7202.2013.12.008 |
中文关键词: 血脂异常 中药 作用机制 心脑血管疾病 |
English Keywords:Chinese herb and formulas Hypolipidemic Mechanism Cardiovascular and cerebrovascular disease |
基金项目:“重大新药创制”科技重大专项(编号:2009ZX09502-031);国家自然科学基金(编号:81030063,81303150);国家中医药管理局中医药行业科研专项(编号:200707001,201007001) |
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中文摘要: |
动脉粥样硬化类疾病直接威胁人类健康和生命。降血脂药物的临床应用是心脑血管疾病治疗领域的里程碑,但是随着应用时间的延长及几种降血脂药物的联用,其不良反应如肝损伤、肾损伤、肌肉系统损伤的发大增,因此寻找新的安全有效的降脂药物,成为目前心脑血管疾病防治领域的国际性关注点。传统中药中部分单体和复方具有明确的降血脂、抗动脉粥样硬化的临床疗效,从中筛选出高效、低副作用的降脂药物近年来引起国内外学者的极大关注。本文对近来国内外中药降脂治疗作用的研究进展做一评述。 |
English Summary: |
Atherosclerotic diseases directly threaten people’s health and lives,and oral lipid-lowering drugs are a milestone in the therapy of cardiovascular and cerebrovascular diseases. But along with prolonging treatment by dual or combining usage of several hypolipidemic drugs,the incidence of many adverse reactions,such as hepatic injury,nephropathy damages,muscular system damage are increasing. Developing novel classes of lipid-lowering agents possessing high efficiency and fewer adverse effects have been the focus of preventing cardiovascular and cerebrovascular diseases all over the world. Screening the high efficient with fewer adverse effects hypolipidemic drugs from Chinese herb and formulas which has clear effect on serum lipid attracts great attention among scientists. This article reviews the progress of hypolipidemic mechanism of Chinese herb and formulas. |
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