世界中医药
文章摘要
引用本文:任 毅 张振忠 赵洪波 马树梅 李 远 梁斌强 刘宁州 豆小妮 万照良 文 华.溃疡性结肠炎灌肠液治疗溃疡性结肠炎的临床疗效观察[J].世界中医药,2013,8(12):.  
溃疡性结肠炎灌肠液治疗溃疡性结肠炎的临床疗效观察
Observation on Clinical Curative Effect of Kuijie Enema in Treating Ulcerative Colitis
投稿时间:2013-11-28  
DOI:10.3969/j.issn.1673-7202.2013.12.016
中文关键词:  溃疡性结肠炎/中医药疗法  灌肠  IL-1β  TNF-α  Nos-3/eNos
English Keywords:Enema ulcerative colitis  IL-1β  TNF-α  Nos-3/eNos
基金项目:北京市中医药科技基金项目(编号:2008-87)
作者单位
任 毅 张振忠 赵洪波 马树梅 李 远 梁斌强 刘宁州 豆小妮 万照良 文 华 北京石景山区中医医院肛肠科北京100043 
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中文摘要:
      目的:观察中草药灌肠对溃疡性结肠炎的临床疗效。方法:将60例溃疡性结肠炎患者给予自拟灌肠液治疗,检测血清细胞因子水平白介素1β(Interleukin-1β,IL-1β)、肿瘤坏死因子(Tumor Necrosis Factor-α,TNF-α)、一氧化氮合酶-3(内皮型)(Nitric Oxide Synthase-3,Nos-3/eNos)的变化趋势以观察中草药液灌肠对溃疡性结肠炎的临床疗效。结果:治疗1个疗程后,总有效率达93.33%,IL-1β平均提升了19.7%,TNF-α平均降低了14.7%,Nos-3/eNos平均降低了20.8%。结论:溃疡性结肠炎灌肠液在防治溃疡性结肠炎方面,疗效可靠,使用方便,造价低廉,值得临床推广。
English Summary:
      To observe the clinical curative effects of Chinese herbal medicine enema in treating ulcerative colitis. Methods:Sixty patients with ulcerative colitis were given the treatment of self-made enema. They were given the detection of serum cytokines,such as IL-1 β,TNF- α and Nos-3/eNos to observe the clinical curative effects of the Chinese herbal medicine enema on ulcerative colitis. Results:After a course of treatment,the total effective rate was 93.33%. The level of IL-1β was promoted by 19.7% on average,and the level of TNF- α was reduced by an average of 14.7%. The level of Nos-3/e Nos was decreased by 20.8%.Conclusion:In the treatment of UC,Chinese medicine Kuijie enema shows the advantages of reliable curative effect,easy application,and low cost,which is worth of clinical application.
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