| 引用本文:马 开 慧.步长脑心通胶囊对急性冠脉综合征的血脂水平以及超敏C反应蛋白的影响[J].世界中医药,2013,8(12):. |
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| 步长脑心通胶囊对急性冠脉综合征的血脂水平以及超敏C反应蛋白的影响 |
| Buchang Naoxintong Capsule on Blood Lipid Level in Acute Coronary Syndrome and Hypersensitive C-reactive Protein |
| 投稿时间：2013-07-11 |
| DOI：10.3969/j.issn.1673-7202.2013.12.020 |
| 中文关键词: 脑心通胶囊 急性冠脉综合症 疗效 血脂 超敏C反应蛋白 |
| English Keywords:Effect of Naoxintong capsule Acute coronary syndrome Curative effect Blood lipids High-sensitivity c-reactive protein |
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| 中文摘要: |
| 目的：观察步长脑心通胶囊对急性冠脉综合征(ACS)血脂水平及超敏C反应蛋白(hs-CRP)的影响。方法：将120例ACS患者按数字表法随机分为对照组和观察组各60例，对照组给予常规治疗，观察组在对照组基础上联合步长脑心通胶囊治疗，观察1个治疗周期后两组主要不良心血管事件(MACE)及血脂、hs-CRP血清水平变化情况。结果：观察组MACE发生率5.00%明显低于对照组18.33%，差异有统计学意义(P<0.05);观察组血脂及hs-CRP均较对照组改善更为明显，差异均有统计学意义(P<0.05);两组不良反应发生率差异无统计学意义(P>0.05)。结论：步长脑心通胶囊可安全、强效纠正ACS患者血脂异常，抑制炎症反应，显著降低MACE发生，检验科为临床诊治ACS的疗效观察提供及时有效的保障。 |
| English Summary: |
| To observe Buchang Naoxintong capsule in patients with acute coronary syndrome (ACS) lipids and effects on high sensitivity c-reactive protein (HS-CRP). Methods：One hundred and twenty patients with ACS were randomly assigned to a control group (n=60) observation group (n=60) according to digital meter method. The control group gave patients conventional treatment，and patients in the observation group gave patients extra Buchang Naoxintong. The major adverse cardiovascular events (MACE) and changes in blood lipids，serum hs-CRP levels of the two groups were observed after one treatment period. Results：The occurrence rate of MACE in the observation group was 5%，which was significantly lower than 18.33% of the control group (P<0.05); the improvements in lipid and hs-CRP are more obvious than those of the control group，showing statistically significant difference (P<0.05); there was statistically significant difference between the two groups in the incidence of adverse reactions (P>0.05). Conclusion：Buchang Naoxintong capsule works safely to relieve dyslipidemia in patients with ACS，and it can inhibit inflammation and significantly reduce occurrence of MACE. It provides timely and effective protection for clinical observation of ACS. |
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