| 引用本文:王秀宝 张季青 陈月玲 陈秋妮 刘秋兰.盆炎灌肠方对盆腔炎性疾病的临床疗效及作用机理探讨[J].世界中医药,2014,9(02):. |
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| 盆炎灌肠方对盆腔炎性疾病的临床疗效及作用机理探讨 |
| The Exploration of Efficacy of TCM Clyster in the Treatment of Pelvic Inflammation and Mechanism of Action |
| 投稿时间：2013-04-05 |
| DOI：10.3969/j.issn.1673-7202.2014.02.016 |
| 中文关键词: 中药保留灌肠 盆腔炎性疾病 临床综合疗效 中医临床症候的疗效 安全性 |
| English Keywords:TCM Clyster Pelvic inflammation Clinical overall efficacy TCM symptoms efficacy Safety |
| 基金项目:福建省泉州市科技局重点课题(编号：Z20100159) |
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| 中文摘要: |
| 目的：观察盆炎灌肠方保留灌肠治疗盆腔炎性疾病的临床疗效。方法：将入选的120例患者随机分为4组，每组30例，A组予盆炎灌肠方保留灌肠，B组予口服蒲皂愈炎汤，C组予口服蒲皂愈炎汤并保留灌肠，D组予奥硝唑分散片。结果：经14 d治疗后，A组、B组、C组的中医临床痊愈率、显效率和总有效率均明显优于D组(P<0.05或P<0.01)。A组与C组的显效率分别为50.00%和53.33%(P>0.05)；A、C组与B组比较(P<0.05或P<0.01)。总有效率依次为C组93.33%、A组90.00%、B组76.67%、D组66.67%，A组与C组比较(P>0.05)；A、C组与B组比较(P<0.05或P<0.01)。表明A组和C组的疗效明显优于B组和D组。4组患者治疗后的局部体征评分、疼痛评分、止痛疗效及中医症状评分均较治疗前明显改善(P<0.05或P<0.01)。止痛疗效A组、B组、C组、D组的总有效率依次为86.67%、76.67%、83.33%和73.33%，A组优于其他3组。A组有2例、C组有1例于1~3 d时出现肛门口轻微不适感，未经特殊处理自行好转；D组有7例有恶心感，加服维生素B6后改善。表明A组无明显不良反应；治疗费4组从少到多依次为D组2.59×14=87.63(元)、A组8.41×14=114.94(元)、B组10.7×14=149.94(元)、C组的费用(8.41+10.7)×14=264.74(元)。结论：盆炎灌肠方保留灌肠治疗盆腔炎性疾病的作用独特、疗效确切、费用低廉。 |
| English Summary: |
| To observe the clinical curative effect of TCM Clyster on pelvic inflammation.Methods：the 120 patients were randomized into 4 arms：A， B， C and D， 30 cases in each arm.We gave TCM Clyster to Arm A， Puzao Yuyan Decoction to Arm B， TCM Clyster and Puzao Yuyan Decoction to Arm C， Ornidazole dispersible tablet to Arm D.Results：After treatment for 14 consecutive days， the recovery rate， significant effective rate and total effective rate of Arm A， B and C were significantly higher than that of Arm D (P<0.05 orP<0.01).The significant effective rate of Arm A and C were 50.00% and 53.33%(P>0.05)， having statistical significance compared with Arm B (P<0.05 orP<0.01).The total effective rate of Arm C， A， B and D were respectively 93.33%， 90.00%、，76.67% and 66.67%.Arm A was not statistically different than Arm C， however both arms were significant than Arm B (P<0.05 orP<0.01)， which indicated that the efficacy of Arm A and C was superior to Arm B and D.After treatment， all the arms improved in terms of local symptoms， pain score， analgesic efficacy and TCM symptom score(P<0.05 orP<0.01).The total effective rate of analgesic efficacy of Arm A.B，C and D were respectively 86.67%、76.67%、83.33% and 73.33%.2 patients in Arm A and 1 patient in Arm C felt slight discomfort in the anus at day1 - 3， which recovered spontaneously without corrective treatment.7 patients in Arm D felt nauseated， which was relieved after taking vitamin B6.Patients in Arm A reported no obvious adverse reactions.Costs of treatment：Arm D：￥87.63， Arm A：￥114.94， Arm B：￥ 149.94， Arm C ：264.74.Conclusion：TCM Clyster is effective to treat pelvic inflammation， and less expensive compared to other treatments in this research. |
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