| 引用本文:王雪飞 李 彬 刘清泉 郭玉红.脓毒症相关性脑病的发病机制及治疗探讨[J].世界中医药,2014,9(03):. |
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| 脓毒症相关性脑病的发病机制及治疗探讨 |
| Exploration on Pathogenesis of Sepsis-Associated Encephalopathy |
| 投稿时间：2014-02-17 |
| DOI：10.3969/j.issn.1673-7202.2014.03.005 |
| 中文关键词: 脓毒症 脑病 发病机制 |
| English Keywords:Spesis Encephalopathy Pathogenesis |
| 基金项目:国家“十二五”科技重大专项（编号：2013ZX09102026） |
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| 中文摘要: |
| 脓毒症(spesis)是由感染引起的全身炎症反应综合征，脓毒症相关性脑病(Sepsis-Associated Encephalopathy，SAE)是脓毒症引起的弥漫性脑功能障碍，主要表现为精神状态和运动功能的改变，包括神智异常、昏迷、激动及活动减少等。近年来，脓毒症的研究不断深入，但脓毒症相关性脑病的研究和报道相对较少，目前该病发病机理尚不明确，诊断标准存在争论，治疗上主要直接针对脓毒症，对脑损伤尚无特效疗法，预后较差。深入研究脓毒症相关性脑病的发病机制，探讨该病的有效疗法将有助于提高患者生存质量，减轻家庭和社会的负担，提升危重疾病的临床诊疗水平。 |
| English Summary: |
| Spesis is a systemic inflammatory response syndrome caused by infection. Sepsis-Associated Encephalopathy is a diffusive brain dysfunction induced by sepsis, which mainly manifests changes on mental stasis and motor function, including abnormal mental ability, coma, agitation, and motion reduction. Recently, studies on sepsis are getting deeper, but the reports on SAE are few. For now, there is still argument towards diagnosis criteria and there is no definitely effective treatment with good prognosis. It needs deeper studies on the pathogenesis of SAR to explore effective therapy to improve the quality of life of patients, alleviate burdens on families and society, as well as promote the clinical treatment level on serious diseases. |
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