To observe the therapeutic effect of TCM on NASH based on the theory of constitution being adjustable.Methods：Eighty patients with nonalcoholic steatohepatitis of phlegm-blood stasis constitution were screened and divided into control group (n=40) and treatment group(n=40). Patients in both groups were treated with suitable diet and exercise called as foundation therapy. Treatment group gave patients TCM of Yiganjiedu formula. Control group applied silymarin(SM). The courses of treatment of both groups were 3 months. The changes of constitution scores, hepatic function and blood fat were observed to evaluate. Drugs that potentially affect liver function and serum lipid were not allowed to use during the observation period.Results：The results of constitution scores between control group and treatment group had statistically significant differences (P<0.05).The comparisons of hepatic function between the two groups had statistically significant differences (P<0.05).The total effective rate of treatment group was 75.00%, and that of the control group was 52.25%. The results had statistical significance (P<0.01). Conclusion：The treatment of TCM can significantly regulate constitution scores and reduce levels of ALT, AST, GGT, and it has the trend of lowering body mass index (BMI) and blood lipid.