To evaluate the effect of Qingfeichengqi granules on the lung and bowel function of patients with bowel repletion and ALI/ARDS, as well as the relevance between the lung function and bowel function. Methods： A prospective, multi-center, random, double minded and controlled trial was conducted. Two hundred and seven patients who had abdominal diseases manifested with yangming bowel repletion and lung damage treated in the 5 centers from August 2009 to July 2013 were include and randomly divided into treatment group and control group. Patients in the treatment group were given conventional western medicine treatment, and treatment group gave patients extra application of Qingfeichengqi granules. The oxygen index, L/M, APACHE II score before treatment and 7 days after treatment, as well as mortality rate after 7days of treatment were observed. Conclusion： Qingfeichegnqi granules treating patients with abdominal diseases manifested with yangming bowel repletion and lung damage can improve the oxygen rate and bowel function, decrease mortality, and verify the close relevance between lung function and bowel function so that prove the “exterior-interior relation between lung and large intestine”.