世界中医药
文章摘要
引用本文:康 娜1 贾 玫1 王晓星2 赵玮璿1 李 雁1 杜怀棠1.加味逍遥颗粒对肿瘤相关性抑郁患者血清IGF-1的影响[J].世界中医药,2014,9(04):.  
加味逍遥颗粒对肿瘤相关性抑郁患者血清IGF-1的影响
Effect of Modified Xiaoyao Granules on the Serum IGF-1 in Tumor Patients
投稿时间:2013-11-27  
DOI:10.3969/j.issn.1673-7202.2014.04.014
中文关键词:  恶性肿瘤  肿瘤相关性抑郁  加味逍遥颗粒  IGF-1
English Keywords:Tumor  Cancer-related depression(CRD)  Modified Xiaoyao granule  IGF-1
基金项目:北京中医药大学自主选题项目(编号:2010JYB22-JS055)
作者单位
康 娜1 贾 玫1 王晓星2 赵玮璿1 李 雁1 杜怀棠1 1 北京中医药大学东直门医院血液肿瘤科,北京,100700
2 北京市普仁医院中医科,北京,100062 
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中文摘要:
      目的:观察加味逍遥颗粒对肿瘤患者血清胰岛素样生长因子-1(Insulin-like Growth Factor-1,IGF-1)的影响,探讨血清IGF-1与肿瘤相关性抑郁的关系。方法:采用自身前后对比法,以血清IGF-1水平为观察指标。结果:治疗前后肿瘤相关性抑郁患者血清IGF-1水平下降,P<0.05(P=0.041),具有统计学意义。结论:加味逍遥颗粒能够降低肿瘤患者血清IGF-1水平,IGF-1与肿瘤相关性抑郁呈正相关。
English Summary:
      To observe the effect of modified Xiaoyao granules on the serum IGF-1 of tumor patients, and explore the relationship between tumor related depression and serum IGF-1. Methods: Comparison before-after study, and the level of serum IGF-1 was observed. A total of 64 patients with cancer related depression were given continuous treatment of 2 courses (14 days for a course). Results: The serum IGF-1 level of cancer-related depression patients before treatment was obviously higher than that of normal small samples; after 28 days treatment, serum IGF-1 level of patients decreased, with statistical significance, P<0.05(P=0.041). Conclusion: Modified Xiaoyao granules can reduce IGF-1 level. Verification of IGF-1 and cancer related depression is positively relevant.
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