世界中医药

目的：观察中西医结合法治疗类风湿性关节炎的临床疗效。方法：选取我院2008年5月至2012年10月收治的80例类风湿性关节炎患者按照随机数字表法随机分为治疗组与对照组各40例，两组患者均给予常规西药治疗，包括甲氨蝶呤10 mg口服，1次/d;双氯芬酸钠缓释片75 mg口服，1次/d。治疗组在上述治疗基础上加用自拟“温阳通痹汤”加减治疗，治疗1个疗程(8周)后比较临床疗效。结果：治疗1个疗程后，治疗组治愈17例、显效16例，愈显率为82.5%;对照组治愈8例，显效15例，愈显率为57.5%。治疗组愈显率显著高于对照组(χ2=11.052，P<0.01)。两组患者治疗前关节压痛指数、关节肿胀指数、晨僵时间及ESR、CRP各项指标比较差异无统计学意义(P>0.05)，治疗1个疗程后治疗组均较治疗前、对照组上述指标均改善明显(P<0.05)，具有统计学意义。结论：应用中西医结合法治疗类风湿性关节炎效果理想，值得推广应用。

English Summary:

To observe the clinical efficacy of integrative treatment of rheumatoid arthritis.Methods：In our hospital， 80 cases of patients in May 2008 to October 2012 with rheumatoid arthritis according to the random number table， randomly divided into treatment group(n=40) and control group(n=40)，patients were treated with conventional medicine， including methotrexate 10mg orally，1 qd;diclofenac sodium tablets 75mg orally，1 qd.Treatment group therapy based on the use of " wen yang tong bi soup" Treating，comparing two groups` clinical efficacy after 8 weeks(a course of treatment).Results：After one course of treatment，in treatment group，17 cases were cured， effective in 16 cases，markedly effective rate was 82.5%;In control group，8 patients were cured， 15 cases markedly，markedly effective rate was 57.5%.Markedly effective rate of the treatment group was significantly higher (χ2=11.052，P<0.01).Before treatment， joint tenderness index，joint swelling index，duration of morning stiffness and ESR，CRP indicators of two groups` patients， showed no significant difference (P>0.05)，while after treatment， these index of treatment group were improved significantly comparing with before treatment， and with the control group(P<0.05).Conclusion：The clinical efficiency of integrative treatment of rheumatoid arthritis is satisfactory，and should be widely applied.

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