Standardized Biobank is an important guarantee for the rapid industrialization and clinical application of the research achievements. Meanwhile, it is also a crucial part and assurance in the independent innovation system of life science and biomedical technology. The paper aims to analyze the current situation, trends and problems in the construction of Biobank based on its concept, function and construction progress. The construction elements of Biobank were discussed in detail from the aspects ofcollection of sample, methods and traceability, ethical problems, facilities and environment, system management and so on. And the present management standard about Biobank was listed as well. The exploration aims to provide some reference for the Biobank construction and development of National Clinical Research Base of Traditional Chinese Medicine.