Chronic kidney disease (CKD) has become a major global public health problem， the increasing occurrence of Acute kidney injury (AKI) accomanying CKD has also drawn increasing attention from the society.In recent years， many researchers did researched on various aspects of the disease， such as the preventing the AKI occurrence， improving the prognosis， making significant progress.This research did a literatre review of recent research on the concept of A on C， the biomarkers， the pathogenesis and the treatment by combined Chinese and Western medicine.