Abstract:Cardiovascular disease is characterized by the high prevalence and low cure rate, and has become the leading cause of death.Its development is a complex progress involving multiple steps, multiple phases and multiple factors.The western medicine can act on one target for one disease and has a certain efficacy.Traditional Chinese medicine (TCM) can act on multiple targets and pathways, which causes a lasting and mild effect.The combinatorial application of Chinese and Western medicine can treat the disease from many ways to enhance the efficacy and reduce the side effects.This paper focuses on the strategies of integrated application of Chinese and Western medicine for cardiovascular diseases, and presents three strategies which are "TCM as the major, Western medicine as the minor; Western medicine as the major, TCM as the minor; Chinese and western medicine equally important" so as to provide a reference for the clinical use of drugs and new drug research and development.